Endocrine Abstracts

Reduced vitamin D levels are a prevalent clinical finding that is clearly associated with increased morbidity and mortality. There is considerable controversy, however, as to how much vitamin D is required for the effective vitamin D replenishment in patients with reduced vitamin D levels.Therefore, we decided to evaluate the effectiveness of 1000 to 3000 U qd of vitamin D and of vitamin D receptor agonists (VDRA) in 161 patients with vitamin D levels &#...

There are still considerable deficits in the prevention of cardiovascular diabetes complications as in effective antihypertensive treatment in type 2 diabetic patients in daily practice. There is controversy, however, to which extent lack of information regarding potential risk factors or deficits in disease awareness of the patients themselves contributes to this unfavourable situation.In 45 female and 51 male type 2 diabetic patients, age, 56+16...

Postprandial hyperglycaemia is a cardiovascular risk factor in diabetic patients. Therefore, younger type 2 diabetic patients are best treated by intensified insulin therapy (IIT) for effective control of postprandial hyperglycaemia. It is unclear, however, whether rapid acting insulin analogues were superior to normal human insulin when used in IIT by patients with type 2 diabetes mellitus.We carried out a randomised open intra-individual cross-over tri...